Manipulation Microparticle Polystyrene Microparticles as Handles
نویسنده
چکیده
Varun Saxena Using a fixed beam with a fundamental Gaussian mode, a gradient force optical trap was used to translate a single cell using a carboxylated polystyrene bead as a handle. Currently, the force with which the optical trap can manipulate an individual cell alone is very weak. In fact, the inadequate nature of the optical trap on living cells has prevented this technique from being useful in most research involving single cells. However, under the experimental setup used here, the trapping force of a particular neuronal cell line, CATH.a, was increased by over 270% by using carboxylated polystyrene beads as a handle. As a result, optical trapping is now a feasible technique for noninvasively translating individual cells during research.
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تاریخ انتشار 2012